Submissions from 2020
Potential role of cellular senescence on coronavirus infections, Prem Cheapagain
Potential RNA-dependent RNA polymerase inhibitors as prospective therapeutics against SARS-CoV-2, Rudramani Pokhrel, Prem Chapagain, and Jessica Siltberg-Liberles
Faculty Publications from 2019
Clitoria ternatea Flower Petal Extract Inhibits Adipogenesis and Lipid Accumulation in 3T3-L1 Preadipocytes by Downregulating Adipogenic Gene Expression, Poramin Chayaratanasin, Allen Caobi, Chaturong Suparpprom, Sudarat Saenset, Porntip Pasukamonset, Nipattra Suanpairntr, Manuel Alejandro Barbieri, and Sirishai Adisakwattana
Quantitative methods for assessing local and bodywide contributions to Wolbachia titer in maternal germline cells of Drosophila, Steen Christensen, Moises Camacho, Zinat Sharmin, A.J.M. Zahadee Momtaz, Laura Perez, Giselle Navarro, Jairo Triana, Michael Turelli, and Laura Renee Serbus
MATria: a unified centrality algorithm, Trevor Cickovski, Vanessa Aguiar-Pulido, and Giri Narasimhan
Human Sperm Chromosomes: To Form Hairpin-Loops, Or Not to Form Hairpin-Loops, That Is the Question, Dimitirios Ioannou Ph.D. and Helen G. Tempest Ph.D.
Phosphoregulation on mitochondria: Integration of cell and organelle responses, Maribel Lucero, Ana E. Suarez, and Jeremy W. Chambers
Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis, Clara Penas, Maria E. Maloof, Vasileios Stathias, Jun Long, Sze Kiat Tan, Jose Mier, Yin Fang, Camilo Valdes, Jezabel Rodriguez-Blanco, Cheng-Ming Chiang, David J. Robbins, Daniel J. Liebl, Jae K. Lee, Mary E. Hatten, Jennifer Clarke, and Nagi G. Ayad
Aedes aegypti Mosquitoes Detect Acidic Volatiles Found in Human Odor Using the IR8a Pathway, Joshua A. Raji, John S. Casti, Sheyla Gonzalez, Valeria Saldana, Marcus C. Stensmyr, and Matthew DeGennaro
Nanocomposite Bienzymatic Sensor for Monitoring Xanthine in Wound Diagnostics, Sohini RoyChoudhury, Yogeswaran Umasankar, Pulak Bhushan, Penelope A. Hirt, Flor E. MacQuhae, Luis J. Borda, Hadar A. Lev-Tov, Robert Kirsner, and Shekhar Bhansali
Adapting Flint for Calculating Bacterial Replication Rates in Microbiomes, Vitalii Stebliankin, Camilo Valdes, Kalai Mathee, and Giri Narasimhan
Large scale microbiome profiling in the cloud, Camilo Valdes, Vitalii Stebliankin, and Giri Narasimhan
Submissions from 2018
Vitamin E inhibits the UVAI induction of “light” and “dark” cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes, George J. Delinasios, Mahsa Karbaschi, Marcus Cooke, and Antony R. Young
Submissions from 2017
ATria: a novel centrality algorithm applied to biological networks, Trevor Cickovski, Eli Peake, Vanessa Aguiar-Pulido, and Giri Narasimhan
Allatotropin: A pleiotropic neuropeptide that elicits mosquito immune responses, Salvador Hernández-Martínez, Minerva Sánchez-Zavaleta, Kevin Brito, Antonia Herrera-Ortiz, Sheila Ons, and Fernando G. Noriega
A new model of sperm nuclear architecture following assessment of the organization of centromeres and telomeres in three-dimensions, Dimitirios Ioannou, Nicole Millan, Elizabeth Jordan, and Helen G. Tempest
Synthesizing topological structures containing RNA, Di Liu, Yaming Shao, Gang Chen, Yuk-Ching Tse-Dinh, Joseph A. Piccirilli, and Yossi Weizmann
Modeling the flux of metabolites in the juvenile hormone biosynthesis pathway using generalized additive models and ordinary differential equations, Raúl O. Martínez-Rincón, Crisalejandra Rivera-Pérez, Luis Diambra, and Fernando G. Noriega
How micronutrients influence the physiology of mosquitoes, Crisalejandra Rivera-Pérez, Mark E. Clifton, and Fernando G. Noriega
A Hormonal Signaling Cascade During an Early Adult Critical Period Required for Courtship Memory Retention in Drosophila, Sang Soo Lee, Yike Ding, Natalie Karapetians, Crisalejandra Rivera-Perez, Fernando G. Noriega, and Micheal E. Adams
Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry, Kaveesha J. Wijesinghe, Sarah Urata, Nisha Bhattarai, Edgar E. Kooijman, Bernard S. Gerstman, Prem P. Chapagain, Sheng Li, and Robert V. Stahelin
Submissions from 2016
Metagenomics, Metatranscriptomics, and Metabolomics Approaches for Microbiome Analysis, Vanessa Aguiar-Pulido, Wenrui Huang, Victoria Suarez-Ulloa, Trevor Cickovski, Kalai Mathee, and Giri Narasimhan
RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals, Muzammil Ahmad, Yutong Xue, Seung Kyu Lee, Jennifer L. Martindale, Weiping Shen, Wen Li, Sige Zou, Maria Ciaramella, Helene Debat, Marc Nadal, Fenfei Leng, Hongliang Zhang, Quan Wang, Grace Ee-Lu Siaw, Hengyao Niu, Yves Pommier, Myriam Gorospe, Tao-Shih Hsieh, Dongyi Xu, and Weidong Wang
Investigating direct interaction between Escherichia coli topoisomerase I and RecA, Srikanth Banda, Purushottam Babu Tiwari, Yesim Darici, and Yuk-Ching Tse-Dinh
Identification of proximal sites for unwound DNA substrate in Escherichia coli topoisomerase I with oxidative crosslinking., Bokun Cheng, Qingxuan Zhou, Liwei Weng, John D. Leszyk, Marc M. Greenberg, and Yuk-Ching Tse-Dinh
Wolbachia Endosymbionts Modify Drosophila Ovary Protein Levels in a Context-Dependent Manner, Steen Christensen, Ricardo Perez Dulzaides, Victoria E. Hedrick, A. J. M. Zehadee Momtaz, Ernesto S. Nakayasu, Lake N. Paul, and Laura R. Serbus
Functional Diversification after Gene Duplication: Paralog Specific Regions of Structural Disorder and Phosphorylation in p53, p63, and p73, Helena G. Dos Santos, Janelle Nunez-Castilla, and Jessica Siltberg-Liberles
Paralog-Specific Patterns of Structural Disorder and Phosphorylation in the Vertebrate SH3–SH2–Tyrosine Kinase Protein Family, Helena G. Dos Santos and Jessica Siltberg-Liberles
DNA supercoiling, a critical signal regulating the basal expression of the lac operon in Escherichia coli, Geraldine Fulcrand, Samantha Dages, Xiaoduo Zhi, Prem Cheapagain, Bernard S. Gerstman, David Dunlap, and Fenfei Leng
Fluorescently labeled circular DNA molecules for DNA topology and topoisomerases, Maxwell Gu, Andrea Berrido, Walter Gonzalez, Jaroslava Miksovska, Jeremy W. Chambers, and Fenfei Leng
Identification of Novel Genomic Islands in Liverpool Epidemic Strain of Pseudomonas aeruginosa Using Segmentation and Clustering, Mehul Jani, Kalai Mathee, and Rajeev K. Azad
Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair, Yanhao Lai, Helen Budworth, Jill M. Beaver, Nelson L.S. Chan, Zunzhen Zhang, Cynthia T. McMurray, and Yuan Liu
The neurotranscriptome of the Aedes aegypti mosquito, Benjamin J. Matthews, Carolyn S. McBride, Matthew DeGennaro, Orion Despo, and Leslie B. Vosshall
Otopathogenic Pseudomonas aeruginosa Enters and Survives Inside Macrophages, Rahul Mittal, Christopher V. Lisi, Hansi Kumari, M'hamed Grati, Patricia Blackwelder, Denise Yan, Chaitanya Jain, Kalai Mathee, Paulo H. Weckwerth, and Xue Z. Liu
Avoiding Regions Symptomatic of Conformational and Functional Flexibility to Identify Antiviral Targets in Current and Future Coronaviruses, Jordon Rahaman and Jessica Siltberg-Liberles
Fast, ultra-trace detection of juvenile hormone III from mosquitoes using mass spectrometry, Cesar E. Ramirez, Marcela Nouzova, Paolo Benigni, Martin Quirke, Fernando G. Noriega, and Francisco Fernandez-Lima
A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα., Shayna Sandhaus, Rosella Taylor, Tiffany Edwards, Alexis Huddleston, Ykeysha Wooten, Ramaiyer Venktraman, Ralph T. Weber, Antonio González-Sarrías, Patrick M. Martin, Patrice Cagle, Yuk-Ching Tse-Dinh, Stephen J. Beebe, Navindra Seeram, and Alvin A. Holder
Insights from the Structure of Mycobacterium tuberculosis Topoisomerase I with a novel protein fold, Kemin Tan, Nan Cao, Bokun Cheng, Andrezej Joachimiak, and Yuk-Ching Tse-Dinh
Allatostatin-C antagonizes the synergistic myostimulatory effect of allatotropin and serotonin in Rhodnius prolixus (Stal), María José Villalobos-Sambucaroa, Luis Animal Diambra, Fernando G. Noriega, and Jorge Rafael Ronderos
Faculty Publications from 2015
A rapid and sensitive high-throughput screening method to identify compounds targeting protein-nucleic acids interactions, Nicole Alonso, Roboan Guillen, Jeremy W. Chambers, and Fenfei Leng
AP endonuclease 1 prevents trinucleotide repeat expansion via a novel mechanism during base excision repair, Jill M. Beaver, Yanhao Lai, Meng Xu, Astrid H. Casin, Eduardo E. Laverde, and Yuan Liu
Inhibitory effect of Clitoria ternatea flower petal extract on fructose-induced protein glycation and oxidation-dependent damages to albumin in vitro, Poramin Chayaratanasin, Manuel Alejandro Barbieri, Nipattra Suanpairintr, and Sirichai Adisakwattana
Inhibition of Zn(II) Binding Type IA Topoisomerases by Organomercury Compounds and Hg(II), Bokun Cheng, Thirunavukkarasu Annamalai, Shayna Sandhaus, Priyanka Bansod, and Yuk-Ching Tse-Dinh
Comparative Analysis of Wolbachia Genomes Reveals Streamlining and Divergence of Minimalist Two-Component Systems, Steen Christensen and Laura Renee Serbus
The mysterious multi-modal repellency of DEET, Matthew DeGennaro
Microbial "social networks", Mitch Fernandez, Juan D. Riveros, Michael Campos, Kalai Mathee, and Giri Narasimhan
The Dimerization State of the Mammalian High Mobility Group Protein AT-Hook 2 (HMGA2), Lorraine Frost, Maria A.M. Baez, Christopher Harrilal, Alyssa Garabedian, Francisco Fernandez-Lima, and Fenfei Leng
Chromosome territory repositioning induced by PHA-activation of lymphocytes: A 2D and 3D appraisal, Dimitirios Ioannou, Lakshmi Kandukuri, Joe Leigh Simpson, and Helen G. Tempest
Impact of sperm DNA chromatin in the clinic, Dimitirios Ioannou, David Miller, Darren K. Griffin, and Helen G. Tempest
Spatial Positioning of All 24 Chromosomes in the Lymphocytes of Six Subjects: Evidence of Reproducible Positioning and Spatial Repositioning following DNA Damage with Hydrogen Peroxide and Ultraviolet B, Dimitrios Ioannou, Lakshmi Kandukuri, Ameer Quadri, Victor Becerra, Joe Leigh Simpson, and Helen G. Tempest
A Novel Insight into Dehydroleucodine Mediated Attenuation of Pseudomonas aeruginosa Virulence Mechanism, Sushmita Mustafi, Maria Luisa Veisaga, L. A. Lopez, and Manuel A. Barbieri
PP2A/B56 and GSK3/Ras suppress PKB activity during Dictyostelium chemotaxis, Marbelys Rodriguez Pino, Boris Castillo, Bohye Kim, and Lou W. Kim
Role of MRP transporters in regulating antimicrobial drug inefficacy and oxidative stress-induced pathogenesis during HIV-1 and TB infections., Upal Roy, Paul Barber, Yuk-Ching Tse-Dinh, Elena V. Batrakova, Debasis Mondal, and Madhavan Nair
The transcription factors Ets1 and Sox10 interact during murine melanocyte development, Amy Saldana-Caboverde; Erasmo M. Perera; Dawn E. Watkins-Chow; Nancy F. Hansen; Meghana Vemulapalli; James C. Mullikin; NISC Compataive Sequencing Program, National Human Genome Research Institute; William J. Pavan; and Lidia Kos
Changes in lipid distribution in E. coli strains in response to norfloxacin, Emily R. Schenk, Frederic Nau, Christopher J. Thompson, Yuk-Ching Tse-Dinh, and Francisco Fernandez-Lima
The Impact of Host Diet on Wolbachia Titer in Drosophila, Laura R. Serbus, Pamela M. White, Jessica Pintado Silva, Amanda Rabe, Luis Teixeira, Roger Albertson, and William Sullivan
Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I, Kemin Tan, Qingxuan Zhou, Bokun Cheng, Zhongtao Zhang, Andrzej Joachimiak, and Yuk-Ching Tse-Dinh
Strain Promoted Click Chemistry of 2- or 8-Azidopurine and 5-Azidopyrimidine Nucleosides and 8-Azidoadenosine Triphosphate with Cyclooctynes. Application to Living Cell Fluorescent Imaging, Jessica Zayas, Marie Annoual, Jayanta K. Das, Quentin Felty, Walter Gonzalez, Jaroslava Miksovska, Nima Sharifai, Akira Chiba, and Stanislaw F. Wnuk
Submissions from 2014
Juvenile Hormone Biosynthesis in Insects: What Is New, What Do We Know, and What Questions Remain?, Fernando G. Noriega
A 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase β., Meng Xu, Yanhao Lai, Zhongliang Jiang, Michael A. Terzidis, Annalisa Masi, Chryssostomos Chatgilialoglu, and Yuan Liu
Submissions from 2013
Dynamics of p53: A Master Decider of Cell Fate, Qingyin Luo, Jill M. Beaver, Yuan Liu, and Zunzhen Zhang
Faculty Publications from 2011
Dehydroleucodin: a guaiane-type sesquiterpene lactone, Horacio A. Priesta, Khalil A. Abboud, Alvaro Velandia, Luis A. Lopez, and Manuel Alejandro Barbieri
