"A Fluorescence-Based Assay for Identification of Bacterial Topoisomera" by Thirunavukkarasu Annamalai, Bokun Cheng et al.
 

A Fluorescence-Based Assay for Identification of Bacterial Topoisomerase I Poisons

Date of this Version

1-1-2018

Document Type

Article

Rights

default

Abstract

Bacterial Topoisomerase I is a potential target for the identification of novel topoisomerase poison inhibitors that could provide leads for a new class of antibacterial compounds. Here we describe in detail a fluorescence-based cleavage assay that is successfully used in HTS for the discovery of bacterial topoisomerase Ι poisons.

DOI

10.1007/978-1-4939-7459-7_18

Identifier

29177747

Plum Print visual indicator of research metrics
PlumX Metrics
  • Citations
    • Citation Indexes: 2
  • Usage
    • Abstract Views: 1
  • Captures
    • Readers: 2
see details

Share

COinS