Date of this Version
4-30-2020
Document Type
Article
Rights
by
Abstract
The disproportionate incidences of COVID-19-related hospitalization and mortality for different age groups and various underlying health conditions is a result of a complex social predisposition to the exposure, resistance, and tolerance for the infection. Based on the observed data as well as the molecular mechanisms for viral entry and replication, cellular senescence related to aging, obesity, hypertension, and diabetes appears to be strongly correlated with the SARS-CoV-2 infections resulting in higher COVID-19 related complications and mortality. Establishing such a correlation may allow us to better explain the pathobiology as well as the differential nature of the SARS-CoV-2 infections and consider targeted control and therapeutic strategies to combat the disease.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Recommended Citation
Cheapagain, Prem, "Potential role of cellular senescence on coronavirus infections" (2020). Coronavirus Research at FIU. 33.
https://digitalcommons.fiu.edu/covid-19_research/33
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Comments
Pre Print Version. Not Peer Reviewed.