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Document Type
Dissertation
Degree
Doctor of Philosophy (PhD)
Major/Program
Biology
First Advisor's Name
Rene Herrera
First Advisor's Committee Title
Committee Chair
Second Advisor's Name
George Duncan
Third Advisor's Name
Ophelia Weeks
Fourth Advisor's Name
Bruce McCord
Fifth Advisor's Name
Alejandro Barbieri
Keywords
Neanderthal, Denisova, Archaic, Hominin, Armenia, Caucasus, AMH, Multiregionalism, Out of Africa
Date of Defense
3-29-2012
Abstract
In the present body of work two primary subjects have been addressed, both individually and in their correspondence, namely 1) the potential for Neanderthals to have contributed to the Modern Human population, and 2) the genetic diversity of one of the most prehistorically impactful human popuations, the Armenians. The first subject is addressed by assessing 1000 mutations in 384 current humans, particularly for those mutations which appear to derive from the Neanderthal lineage. Additionally, the validity of the Neanderthal sequences themselves is evaluated through alignment analysis of fragementary DNA derived from the Vindija Cave sample. Armenian genetic diversity is analyzed through the autosomal short tandem repeats, y-chromsome single nucleotide polymorphisms, and y-chromosome short tandem repeats. The diversity found indicates that Armenians are a diverse group which has been genetically influenced by the various migrations and invasions which have entered their historic lands. Further, we find evidence that Armenians may be closely associated with the peopling of Europe.
Identifier
FI12042318
Recommended Citation
Lowery, Robert K., "Neanderthal Admixture in Current Human Populations" (2012). FIU Electronic Theses and Dissertations. 582.
https://digitalcommons.fiu.edu/etd/582
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