Synthesis and Characterization of Biomimetic Oxo- and Hydroxo-Bridged Dinuclear Copper Pyrazolate Complexes, Their Redox and Oxygen Transfer Chemistry

Authors

Eduardo Mollinedo, Florida International UniversityFollow

Document Type

Dissertation

Degree

Doctor of Philosophy (PhD)

Major/Program

Chemistry

First Advisor's Name

Raphael G. Raptis

First Advisor's Committee Title

Committee chair

Second Advisor's Name

Konstantinos Kavallieratos

Second Advisor's Committee Title

Committee member

Third Advisor's Name

Christopher Dares

Third Advisor's Committee Title

Committee member

Fourth Advisor's Name

Sonia Underwood

Fourth Advisor's Committee Title

Committee member

Fifth Advisor's Name

Jiuhua Chen

Fifth Advisor's Committee Title

Committee member

Keywords

Copper complexes, pyrazolates, inorganic chemistry, alkane oxidation, crystallography

Date of Defense

6-28-2023

Abstract

The project entailed a detailed study of the properties of biomimetic oxo- and hydroxo/alkoxo-bridged dinuclear copper(II) pyrazole complexes. The chemistry of the complexes and their ability to undergo a reversible reduction/oxidation process coupled with oxygen transfer is of great interest, due to their potential applications in industrial catalytic oxygenation as well as their relevance to biological oxidation/oxygenation of organic substrates. The project’s proposed goals included: 1) optimization of the synthesis of dicopper(II) complexes, 2) exploring the synthesis and study of related new dicopper complexes, and 3) the study of their oxygenation/oxidation chemistry. Spectroscopic techniques, such as UV-Vis, Fourier transform infrared (FTIR), were applied to the characterization studies of the complexes, and single-crystal X-ray diffraction for structure determination. Electrochemical studies were carried out in comparison to analogous biological copper-based enzymes and their synthetic models, while spectroscopic and gas chromatographic techniques applied to the systems reveal their catalytic processes. The results of the project are intended to be relevant to biological oxygen delivery systems.

Identifier

FIDC011161

ORCID

https://orcid.org/0009-0005-2349-0748

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

Recommended Citation

Mollinedo, Eduardo, "Synthesis and Characterization of Biomimetic Oxo- and Hydroxo-Bridged Dinuclear Copper Pyrazolate Complexes, Their Redox and Oxygen Transfer Chemistry" (2023). FIU Electronic Theses and Dissertations. 5414.
https://digitalcommons.fiu.edu/etd/5414