Document Type
Dissertation
Degree
Doctor of Philosophy (PhD)
Major/Program
Cognitive Neuroscience
First Advisor's Name
Angela R. Laird
First Advisor's Committee Title
Committee chair
Second Advisor's Name
Isaac Burt
Second Advisor's Committee Title
Committee member
Third Advisor's Name
Stacy L. Frazier
Third Advisor's Committee Title
Committee member
Fourth Advisor's Name
Erica D. Musser
Fourth Advisor's Committee Title
Committee member
Keywords
psychopathology, voxel-based morphometry, anxiety, clinical, meta-analysis, ALE, functional connectivity, development, identity, race
Date of Defense
11-3-2021
Abstract
Anxiety-related disorders are some of the most pervasive mental health disorders affecting adult and youth populations. Despite growing evidence of the neurobiology associated with anxiety-related disorders, a consensus on the neurobiological mechanisms of anxiety-related disorders remains to be elucidated. We first provide background literature on the reasoning behind this dissertation in Chapter 1. In Chapter 2, we conducted a neuroimaging meta-analysis on posttraumatic stress disorder to identify convergent structural and functional alterations associated with this anxiety-related disorder among adults. In Chapter 3, we conducted a neuroimaging meta-analysis to identify convergent structural alterations across diverse groupings of anxiety-related disorders among adults, adolescents, and youth. Chapter 3 included a contrast analysis to examine potential developmental effects of anxiety-related disorders associated with brain structure between adults, adolescents, and youth. In Chapter 4, we conduct an extended functional connectivity analysis to characterize functional profiles of the region of interests (ROIs) identified in Chapter 3. We provide concluding thoughts in Chapter 5. The present collection of studies provides implications for understanding the neurobiology of anxiety-related disorders and brain-based approaches to treatment.
Identifier
FIDC010427
ORCID
https://orcid.org/0000-0002-3325-5451
Recommended Citation
Pankey, Brianna S., "Extended Functional Connectivity of Convergent Structural Alterations Among Anxiety Disorders: A Meta-Analysis and Functional Connectivity Analysis" (2021). FIU Electronic Theses and Dissertations. 4868.
https://digitalcommons.fiu.edu/etd/4868
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