Document Type

Dissertation

Degree

Doctor of Philosophy (PhD)

Major/Program

Public Health

First Advisor's Name

Dr. Miguel Ángel Cano

First Advisor's Committee Title

Committee chair

Second Advisor's Name

Dr. Angelica M. Roncancio

Second Advisor's Committee Title

Committee member

Third Advisor's Name

Dr. Matthew Valente

Third Advisor's Committee Title

Committee member

Fourth Advisor's Name

Dr. Diana M. Sheehan

Fourth Advisor's Committee Title

Committee member

Fifth Advisor's Name

Dr. Gladys Ibañez

Fifth Advisor's Committee Title

Committee member

Keywords

HPV vaccine uptake, emerging adults, Hispanics

Date of Defense

11-12-2021

Abstract

Human Papillomavirus (HPV) infection is the most common sexually transmitted infection in the United States (U.S.). College students are at high risk of developing HPV-related diseases and play key roles in transmitting the infection. Fortunately, HPV-related cancers can be prevented through HPV vaccination.

A cross-sectional study was designed to collect data from convenience samples of Hispanic emerging adults from Florida International University (FIU) in Miami, Florida, and the University of Houston (UH) in Houston, Texas. Participants who were 18-26 years old, self-identified as Hispanic or Latino/a, able to read English, and enrolled in FIU or UH were included in the study. The study was approved by the Institutional Review Board at FIU and UH. All data analyses were performed in SPSS v22.Three independent multivariable logistic regression models were used to examine the association between focal predictors and HPV vaccine uptake.

Of the available 770 participants, 87% were from FIU and 13% were from UH. The first model examined the association between cancer fatalism and HPV vaccine uptake and the moderation effect of HPV knowledge and HPV vaccine knowledge. The study found a significant association between cancer fatalism and HPV vaccine uptake among FIU participants (aOR: 0.96; 95% CI 0.92 – 0.99) but no significant association was found among UH participants. The study did not observe any moderating effect among FIU and UH participants. The second multivariable logistic regression model assessed the association between traditional gender roles and HPV vaccine uptake and the moderating effect of acculturation. The study found a significant association between traditional gender roles and HPV vaccine uptake among FIU participants (aOR: 0.94; 95% CI 0.89 – 0.99), but did not find an association among UH participants. The interaction effect was not significant in FIU and UH. The third multivariable logistic regression model examined the association between familism and HPV vaccine uptake after adjusting for the potential confounders. The study found no significant association between familism and HPV vaccine uptake among FIU and UH participants.

The findings from this study suggest an association between sociocultural factors and HPV vaccine uptake among Hispanic emerging adults, which differed by study site. Many adolescents and young adults remain unvaccinated in the U.S. Future interventions should be designed to provide culturally relevant HPV vaccine education to emerging adults.

Identifier

FIDC010453

ORCID

0000-0001-9222-9838

Included in

Epidemiology Commons

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