Document Type

Thesis

Degree

Master of Science (MS)

Major/Program

Biomedical Engineering

First Advisor's Name

Juan Franquiz

First Advisor's Committee Title

Committee Chair

Second Advisor's Name

Anthony J. McGoron

Third Advisor's Name

Eric T. Crumpler

Date of Defense

7-24-2003

Abstract

This thesis involves a procedure, which calculated and compared the sum of all the pixel counts, threshold pixel counts sum of a 3D PET image and mean and maximum pixel count of one single transaxial slice (2D) of simulated tumors for a chosen region of interest (ROI). A calibration factor was multiplied by the sum of the pixel counts, threshold pixel counts sum of all the transaxial slices, and the mean, and maximum pixel counts of one single transaxial slice in an ROI to calculate for the activity of the tumor. This activity calculated was compared with the real activity values. The results showed that the sum of all the pixel counts with applied threshold is better to calculate the activity of tumor with greater accuracy.

These findings suggest that a 3D distribution of sum of all the pixel counts was able to calculate the activity of malignant tumors and lung lesions with better accuracy.

Identifier

FI15101249

Comments

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