Document Type
Thesis
Degree
Master of Science (MS)
Major/Program
Biology
First Advisor's Name
Fernando G. Noriega
First Advisor's Committee Title
Committee Chair
Second Advisor's Name
Lidia Kos
Third Advisor's Name
Mauricio Rodriguez-Lanetty
Keywords
Juvenile Hormone, corpora allata, Regulation, Aedes aegypti, Mosquito, Ecdysis Triggering Hormone
Date of Defense
1-24-2014
Abstract
Ecdysis triggering hormone (ETH) is a neuropeptide known for its role in the orchestration of ecdysis. However, its role in the regulation of Juvenile Hormone (JH) synthesis is unknown. In Aedes aegypti, JH is synthesized by the corpora allata (CA) and titers are tightly regulated by allatoregulatory factors. In this study I describe the effect of ETH on JH synthesis during the late pupal stage and in the adult female after blood feeding. Analysis of ETH receptor (ETHRs) expression showed that ETHRs are present in both the CA and the corpora cardiaca (CC), a neurohemal organ. The data suggest that ETH regulates JH synthesis directly through its receptors in CA. Our results show that in pupa, ETH has a stimulatory effect on JH synthesis while in adult blood fed females, ETH is inhibitory. These findings constitute the first evidence of ETH as a regulatory peptide in mosquito JH synthesis.
Identifier
FI14040812
Recommended Citation
Areiza, Maria, "Ecdysis Triggering Hormone and its Role in Juvenile Hormone Synthesis in the Yellow-fever Mosquito, Aedes aegypti" (2014). FIU Electronic Theses and Dissertations. 1147.
https://digitalcommons.fiu.edu/etd/1147
Included in
Biology Commons, Cellular and Molecular Physiology Commons, Comparative and Evolutionary Physiology Commons, Molecular Biology Commons
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