Novel MIPs-Parabens based SPE Stationary Phases Characterization and Application

Authors

Angela Tartaglia, University of Chieti–Pescara “G. d’Annunzio"
Abuzar Kbir, International Forensic Research Institute and Department of Chemistry and Biochemistry, Florida International UniversityFollow
Songhul Ulusoy, Cumhuriyet University
Halil Ibrahim Ulusoy, Cumhuriyet University
Giuseppe Maria Merone, University of Chieti–Pescara “G. d’Annunzio”
Fabio Savini, Pharmatoxicology Laboratory—Hospital “Santo Spirito”
Cristian D'Ovidio, University of Chieti–Pescara “G. d’Annunzio”
Ugo de Grazia, IRCCS Neurological Institute Foundation Carlo Besta
Serena Gabrielli, University of Camerino
Fabio Maroni, University of Chieti–Pescara “G. d’Annunzio”
Pantaleone Bruni, University of Chieti–Pescara “G. d’Annunzio”
Fausto Croce, University of Chieti–Pescara “G. d’Annunzio”
Dora Melucci, University of Bologna
Kenneth G. Furton, International Forensic Research Institute and Department of Chemistry and Biochemistry, Florida International UniversityFollow
Marcello Locatelli, University of Chieti–Pescara “G. d’Annunzio”

Date of this Version

9-13-2019

Document Type

Article

Abstract

In this work, the synthesis, characterization, and application of novel parabens imprinted polymers as highly selective solid-phase extraction (SPE) sorbents have been reported. The imprinted polymers were created using sol–gel molecular imprinting process. All the seven parabens were considered herein in order to check the phase selectivity. By means of a validated HPLC-photodiode array detector (PDA) method all seven parabens were resolved in a single chromatographic run of 25 min. These SPE sorbents, in-house packed in SPE empty cartridges, were first characterized in terms of extraction capability, breakthrough volume, retention volume, hold-up volume, number of theoretical plates, and retention factor. Finally, the device was applied to a real urine sample to check the method feasibility on a very complex matrix. The new paraben imprinted SPE sorbents, not yet present in the literature, potentially encourage the development of novel molecularly imprinted polymers (MIPs) to enhance the extraction efficiency, and consequently the overall analytical performances, when the trace quantification is required.

Comments

Originally published in Molecules.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

Recommended Citation

Tartaglia, Angela; Kbir, Abuzar; Ulusoy, Songhul; Ulusoy, Halil Ibrahim; Merone, Giuseppe Maria; Savini, Fabio; D'Ovidio, Cristian; Grazia, Ugo de; Gabrielli, Serena; Maroni, Fabio; Bruni, Pantaleone; Croce, Fausto; Melucci, Dora; Furton, Kenneth G.; and Locatelli, Marcello, "Novel MIPs-Parabens based SPE Stationary Phases Characterization and Application" (2019). Department of Chemistry and Biochemistry. 39.
https://digitalcommons.fiu.edu/chemistry_fac/39