Title
Juvenile Hormone Biosynthesis in Insects: What Is New, What Do We Know, and What Questions Remain?
Date of this Version
10-19-2014
Document Type
Article
Rights
by
Abstract
Our understanding of JH biosynthesis has significantly changed in the last years. In this review I would like to discuss the following topics: (1) the progresses in understanding the JH biosynthesis pathway. Access to genome sequences has facilitated the identification of all the genes encoding biosynthetic enzymes and the completion of comprehensive transcriptional studies, as well as the expression and characterization of recombinant enzymes. Now the existence of different flux directionalites, feed-back loops and pathway branching points in the JH biosynthesis pathways can be explored; (2) the new concepts in the modulation of JH synthesis by allatoregulators. The list of putative JH modulators is increasing. I will discuss their possible role during the different physiological states of the CA; (3) the new theoretical and physiological frameworks for JH synthesis analysis. I will discuss the bases of the flux model for JH biosynthesis. JH plays multiple roles in the control of ovary development in female mosquitoes; therefore, the CA presents different physiological states, where JH synthesis is altered by gating the flux at distinctive points in the pathway; (4) in the final section I will identify new challenges and future directions on JH synthesis research.
DOI
10.1155/2014/967361
Identifier
FIDC001720
Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.
Recommended Citation
Fernando G. Noriega, “Juvenile Hormone Biosynthesis in Insects: What Is New, What Do We Know, and What Questions Remain?,” International Scholarly Research Notices, vol. 2014, Article ID 967361, 16 pages, 2014. doi:10.1155/2014/967361
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