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Document Type

Conference Proceedings

Abstract

Objective: To integrate current evidence on how sleep deprivation and circadian disruption experienced during medical training affect insulin sensitivity, glucose metabolism, and type 2 diabetes risk. Methods: A scoping review was conducted using PubMed and Google Scholar (2010-2025) with the keywords sleep deprivation, circadian rhythm, medical trainees, insulin resistance, and type 2 diabetes. Eligible studies included clinical or experimental research evaluating metabolic or hormonal outcomes in healthcare trainees exposed to shift work or sleep loss. Findings were synthesized thematically by physiological mechanisms and clinical outcomes. Results: Numerous studies indicated that sleep deprivation and circadian disruption were associated with poor metabolic control and regulation. Evidence suggests that inadequate or irregular sleep may influence hormonal balance, inflammatory activity, and glucose control. Findings from healthcare workers and medical trainees indicate that demanding schedules and overnight work could contribute to early markers of insulin resistance and weight gain. Despite the consistency of these trends, long-term data specific to trainee populations remain limited, underscoring the need for further investigation. Conclusion: Circadian disruption and inadequate sleep during medical training appear to impair glucose regulation and may predispose future physicians to metabolic disease. Preventive strategies such as stable scheduling, protected sleep time, and education on sleep hygiene should be integrated into graduate medical education and continued training to mitigate long-term risk.

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