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The role of microbiome is slowly emerging in the field of mental health. Gut microbiome has been related to anxiety, autism, mood disorder and to memory impairments. However its interplay with higher cognition such as Executive Functions (EF) and Emotion Regulation (ER) still remains an open question. Attention Deficit Hyperactivity Disorder (ADHD), a highly prevalent mental disorder, is associated with EF and ER dysfunction. Given that microbiome influences the brain through the release of neurotransmitters such as, dopamine, this study aims to link microbiome with ADHD. Consequently, the proposed project compares participants with ADHD and healthy controls. Fecal samples were collected from each individual using a Gut Kit. Each sample was then analyzed using 16S MiSeq Illumina sequencing to look at the differential abundance of various bacteria. It is hypothesized that the gut microbiome composition will differ between ADHD and the healthy control. The human microbiome is quite malleable, and provided that a link is formed between ADHD and microbiome, a plausible treatment at an earlier developmental stage can be applied.
Akram, Hassan, "Characterizing A Link Between Gut Microbiome and Attention Deficit Hyperactive Disorder" (2017). Honors College Research Collection. 4.
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