Document Type

Thesis

Degree

Master of Science (MS)

Department

Dietetics and Nutrition

First Advisor's Name

Evelyn B. Enrione

First Advisor's Committee Title

Committee Chair

Second Advisor's Name

Kristen Huber

Third Advisor's Name

Beverly A. Warden

Fourth Advisor's Name

Michele W. Keane

Date of Defense

4-3-1995

Abstract

Zn is regularly added to TPN solutions, however, requirements are poorly understood. This research investigated whether or not the route of Zn intake (oral vs parenteral) changes Zn concentration in rat tissues. Twenty-four male Fischer-344 rats were equally and randomly assigned to one of four groups (n=6): control (CON), baseline (BS), orally fed (OF), and intravenously fed (IV). After fifteen days of feeding, organs and sera were collected and analyzed for Zn by atomic absorption spectrophotometry. Of the nine tissues analyzed, the Zn concentrations in the liver, kidney, and lung of the IV rats were significantly higher (p<1.l) than those of the CON, BS, and OF rats. Results indicated that rats fed intravenously with Zn displayed increased Zn concentrations in liver, kidney and lung tissues, and that the concentration of Zn in the serum may not reflect tissue Zn levels. This suggests that the route of Zn intake affects tissue Zn concentration.

Identifier

FI14060812

ORCID

If you are the rightful copyright holder of this dissertation or thesis and wish to have it removed from the Open Access Collection, please submit a request todcc@fiu.edu and include clear identification of the work, preferably with URL.

Share

COinS
 

Rights Statement

Rights Statement

In Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/
This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).