Document Type



Master of Science (MS)


Mechanical Engineering

First Advisor's Name

Richard T. Schoephoerster

First Advisor's Committee Title

Committee Chair

Second Advisor's Name

Ceasar Levy

Third Advisor's Name

James Moore

Date of Defense



Ischemic heart disease, which results from the insufficient coronary artery blood flow is a leading cause of mortality in developed countries. It manifests itself by abnormal left ventricular wall motion during systole.

A three dimensional numerical model was developed to simulate the flow patterns in the left ventricle. Numerical solutions were obtained by discretizing the Navier-Stokes equations for viscous, incompressible, steady flow using finite element method.

A diagnostic index Central Ejection Region (CER) as well as its quantitative version CER coefficient which are based on the flow patterns were defined as the region in which velocity vectors were aligned 5 degrees from the long axis. They seem to be very sensitive to the degrees and size of ischemia.

To validate the numerical method, experimental measurements as well as the numerical computation were performed on sphere-shape normal and the ischemic left ventricle model A good agreement has been achieved.




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