Date of this Version
2024
Document Type
DNP Project
Rights
default
Abstract
Background: Propofol is the most commonly used anesthetic sedative for procedural sedation due to its rapid onset and short duration. However, it has been linked to adverse effects on the cardiovascular and respiratory systems, particularly in high-risk patients with obstructive sleep apnea (OSA).20 Remimazolam, a new intravenous anesthetic sedative, has been proven safe and effective during procedural sedation.6 Recent studies show that remimazolam provides effective sedation, hemodynamic stability, and fewer adverse cardiopulmonary effects, which are beneficial for OSA patients.6
Methods: A comprehensive search utilizing CINAHL, Cochrane Library, and MEDLINE analyzed recent articles on the safety and effectiveness of remimazolam and propofol in patients undergoing procedural sedation. The research included studies comparing propofol with remimazolam in individuals with obstructive sleep apnea and the general population.
Results: The study aimed to improve anesthesia professionals' knowledge about remimazolam and propofol in patients with obstructive sleep apnea who undergo procedural sedation. Nine professionals participated in the educational survey, which showed significant improvements in awareness of the undiagnosed population with OSA and mortality rates associated with propofol during procedural sedation. Understanding of remimazolam's pharmacological characteristics and pharmacokinetics also increased. However, there is still a knowledge gap regarding the impact of propofol on upper airway obstruction, hypoxemia episodes, postoperative complications, and the benefits of remimazolam in patients with OSA.
Recommended Citation
Hernandez, MSN, APRN, FNP-BC, Leyla; Buscemi, PhD, APRN, FNP-BC, Charlie; and Benson, DNP, CRNA, APRN, Joseph, "“Improving the Knowledge among Anesthesia Providers Regarding the Utilization of Remimazolam and Propofol in Patients with Obstructive Sleep Apnea during Procedural Sedation: A Quality Improvement Project.”" (2024). Nicole Wertheim College of Nursing Student Projects. 279.
https://digitalcommons.fiu.edu/cnhs-studentprojects/279
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