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Two-dimensional CuFeSe2 nanosheets have been successfully obtained via solution-phase synthesis using a sacrificial template method. The high purity was confirmed by X-ray diffraction and the two-dimensional morphology was validated by transmission electron microscopy. The in-tense absorption in the 400–1400 nm region has been the basis for the CuFeSe2 nanosheets’ photo-thermal capabilities testing. The colloidal CuFeSe2 (CFS) nanosheets capped with S2− short ligands (CFS-S) exhibit excellent biocompatibility in cell culture studies and strong photothermal effects upon 808 nm laser irradiation. The nanosheets were further loaded with the cancer drug doxorubi-cin and exposed to laser irradiation, which accelerated the release of doxorubicin, achieving synergy in the therapeutic effect.
Liu, Mimi; Radu, Daniela R.; Selopal, Gurpreet Singh; Bachu, Saiphaneendra; and Lai, Cheng Yu, "Stand-alone CuFeSe2 (Eskebornite) nanosheets for photothermal cancer therapy" (2021). All Faculty. 348.