Introduction and Objective: Heart failure is a significant cause of mortality, and type-2 diabetes is a significant risk factor for the development of heart failure. Studies have shown an association between heart failure and diabetes, suggesting that diabetes may be an independent risk factor for mortality due to heart failure. No previous studies have examined the relationship between diabetes and in-hospital mortality in patients with heart failure. Methods: This is a secondary analysis of the Puerto Rico Cardiovascular Disease Surveillance Electronic Database from 2007, 2009, and 2011. A historical cohort, consisting of patients older than 18 years who were hospitalized for decompensated heart failure, was nested into the hospital data. The population of the study is entirely composed of patients 18 years and older who were hospitalized for decompensated heart failure. The outcome included all-cause mortality during hospital stay. Controlling for patient characteristics, we used multivariate logistic regression modeling to assess associations between the outcome and diabetic status. Results: In the years 2007, 2009, and 2011, the Puerto Rico Cardiovascular Disease Surveillance Electronic Database observed 1818 cases of decompensated heart failure. A total of 1632 patients met the inclusion and exclusion criteria and were included in our analysis. Of these, 1031 had diabetes, representing 63.2% of the population, and 601 were nondiabetic, representing 36.8% of the population. The analysis comparing diabetes and mortality rates showed an adjusted OR of 1.3, (95%CI 0.8-2.2, p=0.32). The odds of dying in the hospital from decompensated heart failure in Puerto Rico was not significantly different between diabetics and nondiabetics. Conclusions: We found no association between mortality and diabetic status in patients hospitalized for decompensated heart failure in Puerto Rico. There were some limitations in our study; therefore, further research in this topic is warranted.
Cavitt, Layla; De Los Santos, Yanel; Gates, Matthew; and Zevallos, Juan
"Association of Type-2 Diabetes and In-Hospital Mortality in Puerto Rican Patients Hospitalized with Decompensated Heart Failure,"
Florida Medical Student Research Journal: Vol. 2
, Article 2.
Available at: http://digitalcommons.fiu.edu/fmsrj/vol2/iss1/2