Master of Science
First Advisor's Name
First Advisor's Committee Title
Second Advisor's Name
Third Advisor's Name
Optical Imaging, Breast Cancer Diagnostics, Automation, Optical Tracking, Co-Registration
Date of Defense
The Optical Imaging Laboratory has developed a hand-held optical imaging system that is capable of 3D tomographic imaging. However, the imaging system is limited by longer imaging times, and inaccuracy in the positional tracking of the hand-held probe. Hence, the objective is to improve the performance of the imaging system by improving imaging time and positional accuracy. This involves: (i) development of automated single Labview-based software towards near real-time imaging; and (ii) implementation of an alternative positional tracking device (optical) towards improved positional accuracy during imaging. Experimental studies were performed using cubical tissue phantoms (1% Liposyn solution) and 0.45-cc fluorescence target(s) placed under various conditions. The studies demonstrated a 90% reduction in the imaging time (now ~27 sec/image) and also an increase from 94% to 97% in the positional accuracy of the hand-held probe. Performance enhancements in the hand-held optical imaging system have improved its potential towards clinical breast imaging.
Martinez, Sergio L., "Performance Enhancement In Accuracy and Imaging Time of a Hand-Held Probe-Based Optical Imager" (2011). FIU Electronic Theses and Dissertations. Paper 397.